Real-time prediction of complex physical systems requires surrogate models that learn from data while representing strong multiphysics coupling. Deep Operator Networks have shown success in single-physics problems, yet their effectiveness in capturing nonlinear interactions in coupled systems (such as thermo-mechanical or electro-thermal coupling) remains underexplored. Here we pose a practical question: should the architecture of a neural operator reflect the strength of physical coupling it aims to model? We compare single-branch and multi-branch designs, in both feedforward and sequential recurrent forms, across three representative systems: a reaction-diffusion problem with heterogeneous sources, a nonlinear thermo-electrical problem with temperature-dependent conductivity and Joule heating, and a viscoplastic thermo-mechanical model of steel solidification. Single-branch networks consistently outperform multi-branch variants in tightly coupled regimes by encouraging shared latent representations, whereas multi-branch designs remain favorable for decoupled or single-physics tasks. Once trained, these surrogates deliver full-field predictions up to 1.8 × 104 times faster than physics-based solvers.

The prevailing paradigm in AI for physical systems: scaling general-purpose foundation models toward universal multimodal reasoning, confronts a barrier at the control interface. Frontier vision-language models achieve only 50-53% accuracy on basic quantitative physics tasks, behaving as approximate guessers that preserve semantic plausibility while violating physical constraints. Safety-critical control demands outcome-space guarantees over executed actions, not parameter-space imitation. Here we present a pathway toward domain-specific foundation models through compact language models operating as Agentic Physical AI: policy optimization driven by physics-based simulator validation rather than perceptual inference. We train a 360M-parameter model on synthetic nuclear reactor scenarios scaled from 10^3 to 10^5 examples. Scaling produces strong, regime-dependent reliability gains under nominal simulated conditions, with variance collapse of approximately 500x and elimination of>10% terminal-power excursions on the sampled distribution. Despite balanced exposure to four actuation families, the model concentrates 95% of runtime execution on a single-bank strategy, without reinforcement learning or reward engineering. Representations transfer across simulators without architectural change. We position the system as a candidate decision component within a verification, monitoring, and defense-in-depth architecture, not as a stand-alone safety solution: the demonstrated behavior speaks to closed-loop reliability on a single-step task in simulation and does not yet address off-nominal operation, sensor faults, or uncertainty quantification.

Neural operators have emerged as powerful tools for learning nonlinear mappings between function spaces, enabling real-time prediction of complex dynamics in diverse scientific and engineering applications. With their growing adoption in engineering design evaluation, a wide range of neural operator architectures have been proposed for various problem settings. However, model selection remains challenging due to the absence of fair and comprehensive comparisons. To address this, we propose and standardize six representative 3D industry-scale engineering design datasets spanning thermal analysis, linear elasticity, elasto-plasticity, time-dependent plastic problems, and computational fluid dynamics. All datasets include fully preprocessed inputs and outputs for model training, making them directly usable across diverse neural operator architectures. Using these datasets, we conduct a systematic comparison of four types of neural operator variants, including Branch-Trunk-based Neural Operators inspired by DeepONet, Graph-based Neural Operators inspired by Graph Neural Networks, Grid-based Neural Operators inspired by Fourier Neural Operators, and Point-based Neural Operators inspired by PointNet. We further introduce practical enhancements to adapt these models to different engineering settings, improving the fairness of the comparison. Our benchmarking study evaluates each model strengths and limitations in terms of predictive performance, computational efficiency, memory usage, and deployment complexity. The findings provide actionable insights to guide future neural operator development.

Video-diffusion models have recently set the standard in video generation, inpainting, and domain translation thanks to their training stability and high perceptual fidelity. Building on these strengths, we repurpose conditional video diffusion as a physics surrogate for spatio-temporal fields governed by partial differential equations (PDEs). Our two-stage surrogate first applies a Sequential Deep Operator Network (S-DeepONet) to produce a coarse, physics-consistent prior from the prescribed boundary or loading conditions. The prior is then passed to a conditional video diffusion model that learns only the residual: the point-wise difference between the ground truth and the S-DeepONet prediction. By shifting the learning burden from the full solution to its much smaller residual space, diffusion can focus on sharpening high-frequency structures without sacrificing global coherence. The framework is assessed on two disparate benchmarks: (i) vortex-dominated lid-driven cavity flow and (ii) tensile plastic deformation of dogbone specimens. Across these data sets the hybrid surrogate consistently outperforms its single-stage counterpart, cutting the mean relative L2 error from 4.57% to 0.83% for the flow problem and from 4.42% to 2.94% for plasticity, a relative improvements of 81.8% and 33.5% respectively. The hybrid approach not only lowers quantitative errors but also improves visual quality, visibly recovering fine spatial details. These results show that (i) conditioning diffusion on a physics-aware prior enables faithful reconstruction of localized features, (ii) residual learning reduces the problem, accelerating convergence and enhancing accuracy, and (iii) the same architecture transfers seamlessly from incompressible flow to nonlinear elasto-plasticity without problem-specific architectural modifications, highlighting its broad applicability to nonlinear, time-dependent continua.

`Real-time prediction of complex physical systems requires surrogate models that learn from data while representing strong multiphysics coupling. Deep Operator Networks have shown success in single-physics problems, yet their effectiveness in capturing nonlinear interactions in coupled systems (such as thermo-mechanical or electro-thermal coupling) remains underexplored. Here we pose a practical question: should the architecture of a neural operator reflect the strength of physical coupling it aims to model? We compare single-branch and multi-branch designs, in both feedforward and sequential recurrent forms, across three representative systems: a reaction--diffusion problem with heterogeneous sources, a nonlinear thermo-electrical problem with temperature-dependent conductivity and Joule heating, and a viscoplastic thermo-mechanical model of steel solidification. Single-branch networks consistently outperform multi-branch variants in tightly coupled regimes by encouraging shared latent representations, whereas multi-branch designs remain favorable for decoupled or single-physics tasks. Once trained, these surrogates deliver full-field predictions up to $1.8 \times 10^4$ times faster than physics-based solvers.

Scientific applications increasingly demand real-time surrogate models that can capture the behavior of strongly coupled multiphysics systems driven by multiple input functions, such as in thermo-mechanical and electro-thermal processes. While neural operator frameworks, such as Deep Operator Networks (DeepONets), have shown considerable success in single-physics settings, their extension to multiphysics problems remains poorly understood. In particular, the challenge of learning nonlinear interactions between tightly coupled physical fields has received little systematic attention. This study addresses a foundational question: should the architectural design of a neural operator reflect the strength of physical coupling it aims to model? To answer this, we present the first comprehensive, architecture-aware evaluation of DeepONet variants across three regimes: single-physics, weakly coupled, and strongly coupled multiphysics systems. We consider a reaction-diffusion equation with dual spatial inputs, a nonlinear thermo-electrical problem with bidirectional coupling through temperature-dependent conductivity, and a viscoplastic thermo-mechanical model of steel solidification governed by transient phase-driven interactions. Two operator-learning frameworks, the classical DeepONet and its sequential GRU-based extension, S-DeepONet, are benchmarked using both single-branch and multi-branch (MIONet-style) architectures. Our results demonstrate that architectural alignment with physical coupling is crucial: single-branch networks significantly outperform multi-branch counterparts in strongly coupled settings, whereas multi-branch encodings offer advantages for decoupled or single-physics problems. Once trained, these surrogates achieve full-field predictions up to 1.8e4 times faster than high-fidelity finite-element solvers, without compromising solution accuracy.

Partial differential equations (PDEs) are fundamental to modeling complex and nonlinear physical phenomena, but their numerical solution often requires significant computational resources, particularly when a large number of forward full solution evaluations are necessary, such as in design, optimization, sensitivity analysis, and uncertainty quantification. Recent progress in operator learning has enabled surrogate models that efficiently predict full PDE solution fields; however, these models often struggle with accuracy and robustness when faced with highly nonlinear responses driven by sequential input functions. To address these challenges, we propose the Sequential Neural Operator Transformer (S-NOT), a architecture that combines gated recurrent units (GRUs) with the self-attention mechanism of transformers to address time-dependent,nonlinear PDEs. Unlike S-DeepONet (S-DON), which uses a dot product to merge encoded outputs from the branch and trunk sub-networks, S-NOT leverages attention to better capture intricate dependencies between sequential inputs and spatial query points. We benchmark S-NOT on three challenging datasets from real-world applications with plastic and thermo-viscoplastic highly nonlinear material responses: multiphysics steel solidification, a 3D lug specimen, and a dogbone specimen under temporal and path-dependent loadings. The results show that S-NOT consistently achieves a higher prediction accuracy than S-DON even for data outliers, demonstrating its accuracy and robustness for drastically accelerating computational frameworks in scientific and engineering applications.

Accurate reconstruction of latent environmental fields from sparse and indirect observations is a foundational challenge across scientific domains-from atmospheric science and geophysics to public health and aerospace safety. Traditional approaches rely on physics-based simulators or dense sensor networks, both constrained by high computational cost, latency, or limited spatial coverage. We present the Temporal Radiation Operator Network (TRON), a spatiotemporal neural operator architecture designed to infer continuous global scalar fields from sequences of sparse, non-uniform proxy measurements. Unlike recent forecasting models that operate on dense, gridded inputs to predict future states, TRON addresses a more ill-posed inverse problem: reconstructing the current global field from sparse, temporally evolving sensor sequences, without access to future observations or dense labels. Demonstrated on global cosmic radiation dose reconstruction, TRON is trained on 22 years of simulation data and generalizes across 65,341 spatial locations, 8,400 days, and sequence lengths from 7 to 90 days. It achieves sub-second inference with relative L2 errors below 0.1%, representing a>58,000X speedup over Monte Carlo-based estimators. Though evaluated in the context of cosmic radiation, TRON offers a domain-agnostic framework for scientific field reconstruction from sparse data, with applications in atmospheric modeling, geophysical hazard monitoring, and real-time environmental risk forecasting.

Machine-learning-based surrogate models offer significant computational efficiency and faster simulations compared to traditional numerical methods, especially for problems requiring repeated evaluations of partial differential equations. This work introduces the Geometry-Informed Neural Operator Transformer (GINOT), which integrates the transformer architecture with the neural operator framework to enable forward predictions on arbitrary geometries. GINOT employs a sampling and grouping strategy together with an attention mechanism to encode surface point clouds that are unordered, exhibit non-uniform point densities, and contain varying numbers of points for different geometries. The geometry information is seamlessly integrated with query points in the solution decoder through the attention mechanism. The performance of GINOT is validated on multiple challenging datasets, showcasing its high accuracy and strong generalization capabilities for complex and arbitrary 2D and 3D geometries.

The inverse design of metamaterial architectures presents a significant challenge, particularly for nonlinear mechanical properties involving large deformations, buckling, contact, and plasticity. Traditional methods, such as gradient-based optimization, and recent generative deep-learning approaches often rely on binary pixel-based representations, which introduce jagged edges that hinder finite element (FE) simulations and 3D printing. To overcome these challenges, we propose an inverse design framework that utilizes a signed distance function (SDF) representation combined with a conditional diffusion model. The SDF provides a smooth boundary representation, eliminating the need for post-processing and ensuring compatibility with FE simulations and manufacturing methods. A classifier-free guided diffusion model is trained to generate SDFs conditioned on target macroscopic stress-strain curves, enabling efficient one-shot design synthesis. To assess the mechanical response of the generated designs, we introduce a forward prediction model based on Neural Operator Transformers (NOT), which accurately predicts homogenized stress-strain curves and local solution fields for arbitrary geometries with irregular query meshes. This approach enables a closed-loop process for general metamaterial design, offering a pathway for the development of advanced functional materials.