Abstract This study aimed to investigate the effects of dietary supplementation with modified-hen-egg-yolk on plasma lipids and lipoprotein profiles in rats. During the four-week-experiment, 64 Wistar rats were divided into four groups of 16 (eight of both sexes), and fed commercial rat food (group C); food containing 70% commercial rat mixture and 30% freshly cooked egg yolk originating from laying hen eggs fed with 3% fish oil (group F); 3% palm olein (group P), or 3% lard (group L). The cooked egg yolk in the rat diet affected the concentrations of plasma total and LDL-cholesterol in males of the P and L groups. Cholesterol and total fat in the diet did not have a hypercholesterolemic effect on their own, but when in combination with fatty acid composition, they could contribute to an increase in plasma total and LDL cholesterol concentrations in rats. HDL-cholesterol was the most resilient plasma lipoprotein of rats to dietary treatments in our experiment. Compared to the control group, the addition of hen egg yolk to the rat diet regardless of its quality, adversely affected the values of HDL-C/TC and HDL-C/LDL-C in both males and females.

The endogenous opiate receptor antagonist (naloxone, NAL) and alpha-adrenergic receptor antagonist (dihydroergotoxine, DHETX) were infused separately or simultaneously in dogs to determine their effects in hemonhagic shock. Mean arterial pressure, heart rate, electrocardiogram, respiratory rate, haematocrit and plasma protein concentration were measured during sustained posthemorrhagic hypotension (180 min, 40 mmHg) in 22 dogs. Animals were divided into four groups: DHETX-treated (n=6), NAL-treated (n=5), DHETX+NAL-treated (n=5), and SAL (saline)-treated (control group, n=6). The treatment was performed before bleeding. After 3 hours of posthemorrhagic hypotension, ali shed blood was returned to the dogs, and animals passed through a postretrasfusion period for 60 min. The animals which survived experimental procedure were observed in next 24 hours. Under the present experimental conditions, prophylactic administration of DHETX had better effects on preservation of parameters measured and survival of dogs than NAL, while DHETX+NAL treatment had the worst effects (no one dog survived).