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26. 12. 2022.
Coordinated neurostimulation promotes circuit rewiring and unlocks recovery after spinal cord injury
Functional recovery after spinal cord injury is guided by the formation of new spinal detour circuits. The authors show that the formation of these circuits is enhanced by targeted chemogenetic stimulation of supraspinal and spinal neuron populations. Supraspinal and spinal coordinated stimulation potentiated behavioral recovery.