0
1. 2. 2017.
P041 C-jun n-terminal kinase 2 promotes enterocyte survival and goblet cell differentiation in the inflamed intestine.
Background: c-Jun N-terminal kinases (JNKs) contribute to immune signalling but their functional role during intestinal mucosal inflammation has remained ill definedMethods: Using genetic mouse models we characterized the role of JNK1 and JNK2 during homeostasis and acute colitis. Epithelial apoptos