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R. Rahmanzadeh, M. Weigel, Po-Jui Lu, L. Melie-García, Thanh D. Nguyen, A. Cagol, F. Rosa, M. Barakovic, A. Lutti, Yi Wang, M. Cuadra, E. Radue, L. Gaetano, L. Kappos, J. Kuhle, S. Magon, C. Granziera
18 1. 8. 2022.

A comparative assessment of myelin-sensitive measures in multiple sclerosis patients and healthy subjects

Highlights • qT1 and QSM showed the highest sensitivity to distinguish MS focal WM and cortical pathology from peri-plaque.• MWF and MTsat exhibited the highest sensitivity to NAWM pathology.• qT1 appeared to be the most sensitive measure to NAGM pathology.• All myelin-sensitive qMRI measures exhibited high intra-scanner reproducibility.


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